我的账户 7×24小时客服热线:400-829-7929 语言:
热门产品: 人参皂苷Rh2,人参皂苷Rg3,胡萝卜苷, 木犀草苷
产品分类
在线咨询
联系电话:
销售:
400-829-7929(7*24小时)
028-82633860
028-82633397 
028-
82633165
技术服务和产品定制:
028-82633987
在线服务:  
沈帅 
文静  点击这里给我发消息
贺丹丹  
点击这里给我发消息
      
文献信息

Preformulation Study of 50% Ethanol Extract of Mangosteen Rind (Garcinia mangostana L.)

期刊名:ICHS 2020
文献编号:
文献地址: https://web.archive.org/web/20211018190902id_/https://eudl.eu/pdf/10.4108/eai.26-10-2020.2311315
发表日期:
Garcinia mangostana rind containing alpha-mangostin has the potential to be used as an antioxidant. This study aimed to determine the physicochemical properties and stability of alpha-mangosteen in the 50% ethanol extract of mangosteen rind as a parameter in the pre-formulation study. Physicochemical properties were evaluated for specific and nonspecific extract parameters, determining the optimum wavelength and solubility test. The stability test was carried out at a temperature of 45±5°C with relative humidity 75±5% for 21 days, in acidic and alkaline conditions. The alpha-mangostin content was analyzed using a UV-Vis spectrophotometer. The results showed that the extract was purplish brown, has an aromatic smell, and a bitter taste. The dissolved compound in water and ethanol were 62.54±1.09% and 87.05±0,43%, respectively, the specific density of 5% extract was 1.036, loss on drying 6.66±0,11%, ash content 5.07±0.23%, ash content insoluble in acidic was 0.13±0.02%, alpha-mangosteen content in the extract was 3.85±0.03%. The solubility test showed that alpha-mangosteen in the extract has a solubility value of 1: 16064 in water. The stability test showed that the levels of alphamangostin decreased significantly (p≤ 0.05) at 45±5°C and relative humidity 75±5% for 21 days. Mangosteen rind extract was unstable in the extremely acidic and alkaline conditions.
相关产品