黑芥子苷钾盐

英文名: Sinigrin

中文别名: 黑芥子苷; 芥子苷; 芥子黑苷; 芥子黑糖苷
英文别名: 2-Propenyl glucosinolate; Allyl glucosinolate potassium; Sinigrine
Cas 号: 3952-98-5
产品编码：BP1311
分子式: C10H17NO9S2
分子量: 397.4
来源: 油菜籽(菜粕)等

纯度: 30%, 50%, 90%, 95%, 99%
分析方法: HPLC-DAD or/and HPLC-ELSD
鉴定方法: 质谱（Mass）, 核磁（NMR）
包装: 按客户需求包装。
可以满足克级至公斤级以上大量需求，详情请咨询。

本公司除了提供对照品级别的高纯度黑芥子苷外，还大量提供10%~90%纯度和含量的高品质黑芥子苷，满足客户对于保健品，化妆品等的需求。

References:

1, Sinigrin, a major glucosinolate from cruciferous vegetables restrains non-enzymatic glycation of albumin.

Int J Biol Macromol. 2016 Feb;83:410-5.

Abstract:

Sinigrin is a major component of cruciferous vegetables such as cabbage, Brussels sprout, mustard greens and broccoli. The present study demonstrates the protective effects of sinigrin against the non-enzymatic glycation of albumin and lens crystallin based on fluorescence spectroscopy, circular dichroism and molecular interaction studies. Sinigrin was found to be a potent inhibitor for both the early (Amadori product) and advanced glycation end products (AGEs). In addition, the in vitro glycation studies of lens crystallin demonstrated the strong antiglycation activity of sinigrin. Computational studies using molecular docking approach revealed the interaction pattern of sinigrin with BSA and the binding affinity of sinigrin was found to be greater than the other potent natural inhibitors of glycation such as quercetin, apigenin, and curcumin.

KEYWORDS:

Advanced glycation end products; Albumin; Sinigrin

2, Sinigrin and Its Therapeutic Benefits

Molecules. 2016 Mar 29;21(4):416. 

Abstract:

Sinigrin (allyl-glucosinolate or 2-propenyl-glucosinolate) is a natural aliphatic glucosinolate present in plants of the Brassicaceae family, such as broccoli and brussels sprouts, and the seeds of Brassica nigra (mustard seeds) which contain high amounts of sinigrin. Since ancient times, mustard has been used by mankind for its culinary, as well as medicinal, properties. It has been systematically described and evaluated in the classical Ayurvedic texts. Studies conducted on the pharmacological activities of sinigrin have revealed anti-cancer, antibacterial, antifungal, antioxidant, anti-inflammatory, wound healing properties and biofumigation. This current review will bring concise information about the known therapeutic activities of sinigrin. However, the information on known biological activities is very limited and, hence, further studies still need to be conducted and its molecular mechanisms also need to be explored. This review on the therapeutic benefits of sinigrin can summarize current knowledge about this unique phytocompounds.

KEYWORDS:

Brassicaceae family; anticancer; glucosinolates; mustard; myrosinase; sinigrin

黑芥子苷钾盐的HPLC图谱